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Nerium AD - efficacy, safety and long term use
  • i was recently approached by a long lost 'friend' on facebook whose sole purpose seemed to be to generate interest in selling Nerium AD a new product sold through multi-level marketing and containing extract of oleander of all things.  i told him i would look into the product and let him know.  i am finding it difficult to even conduct independent research because google results for even topics such as 'nerium scam' lead to blogs of 'brand partners' whose goal it appears is to redirect the reader to their sales pitch site.

    paula begoun has a very harsh review of the product which i would take as gospel and there are a couple of MDs who also sell an anti-aging product who have taken on the task of calling the ingredients into question.  you folks are the cosmetic chemists in my world and i trust that i would get solid information from you.  i have already developed a negative perception of the company behind nerium based on their financial statements (my area of expertise as a former general manager of a natural foods store), combined with numerous consumer complaints about the product and the company's failure to honor their money back guarantee, worst of all are the adverse reactions reported by some on sites such as amazon and how 'brand partners' gang up on these reviewers and attempt to sell their product.  i think we all know the pit falls of multi level marketing so the brand partner responses should come as no surprise.

    i think that as cosmetic chemists, you are in a unique position to be able to address the issues of this product's ingredients.  my impression based on information found at beautypedia.com as well as the MDs i mentioned above (bare faced truth -- http://barefacedtruth.com/2012/11/18/when-you-dont-have-the-answer-stonewall-be-a-bully-neriumgate-part-1/) is to stay far, far away from this product because i know my own skin, my rosacea and sensitivity issues and have had to be placed on prednisone in past instances of adverse reactions.  it seems this company not only does not honor it's guarantee but does not even bother to acquire information regarding adverse reactions which i consider to be bad business and unethical.

    i would love to hear your opinions.  the company's website is http://www.nerium.com/default.aspx?ID=www, your opinions on the 'real science' portion would be a great service.  i think the more information that can be put out about potential harm (cell death via oleander extract) the better off consumers will be and i ask for your help here.

    the ingredients as stated by the company's website are below - i am familiar enough with most of them, but again, would appreciate your input.

    NAE-8 Proprietary Blend (Aloe Barbadensis Leaf,
    Nerium Oleander Leaf Extract),

    Aloe Barbadensis Leaf,

    Proprietary Protein
    (Collagen, Elastin, Glycosaminoglycans),

    Oryza Sativa Bran Oil,
    Stearic Acid,
    Cetearyl Glucoside and Cetearyl Alcohol,
    Glycerin,
    C14-22 Alcohol and C12-20 Alkyl Glucoside,
    Glyceryl Stearate,
    Ricinus Communis Seed Oil,
    Cetyl Alcohol,
    Olus Oil,
    Chondrus
    Crispus Powder,
    Sodium Borate,
    Dicaprylyl Ether,
    Hydrolyzed Quinoa,
    Sodium Isostearoyl Lactylate,
    Dimethicone,
    Sodium PCA,
    Proprietary Blend (Caprylyl Glycol, Glycerin,
    Glyceryl Caprylate, Phenylpropanol),
    Parfum,
    Sodium
    Hydroxymethylglycinate,
    Tocopherol

  • thanks right brain - good review there.  i had looked for info using your search feature but got no results - not sure why that is.  thanks again for the response.
  • They sound like douchebags who need to 'accidentally' fall off a ladder. yes i agree the search function sucks.
  • Ditto how sucky our search function is. If I hadn't already fired our IT guy I would have had him look into it. 
  • bummer there on the search function, i would loan you mine, but i'm married to him. :)

    i thought i had made a post here after rozy, but it seems to have disappeared. 

    right brain - would you have any insight into

    • whether the nerium oleander is less toxic than the yellow flowered variety (all i know is when i've called poison control, their advice is the same) and
    • the extract of oleander is oleandrin - correct or no?

    i'm in the midst of a heated discussion on an amazon review for this quack product, have done an enormous amount of research on behalf of a friend who is now selling this stuff and think i have a pretty firm grasp of the basics.  the 'brand partner' wishing to argue can only point me to safety videos posted on the nerium site, but i have a secret stash of cosmetic chemists and MDs to help form my argument.  i personally think this dude's drinking oleander koolaid and selling cell death in an over priced bottle.

  • Toxicity probably similar, as far as I know they're just different varieties of the sames species (white flowering also)

    Oleandrin is a chemical compound from that occurs in the sap of the Oleander tree.  Depending on what part of the plant and the extraction method it would occur in an extract at some concentration.

    How toxic something is depends on route of exposure, something that is applied topically wont necessarily have the same effect as it does when taken orally.

  • thanks for the info, alchemist. 

    i'm aware that the toxicity would vary based on how the toxin was encountered - whether ingested, applied to skin, i have read that inhalation of burning oleander can be hazardous.

    the medical information regarding cancer treatment with oleander derivitives indicates some level of efficacy by destruction of cells (as would say chemotherapy, i'm a cancer survivor and understand that mechanism well).  as far as i can tell, oleander as a cardiac glycoside causes cell death and oxidation. 

    if we take it as a known fact that anti-oxidents are powerful anti-aging ingredients, would not oleander be just the opposite?

    sorry if i am being pesky, i have been doing some hard core research on this in order to get a friend away from this product and company ASAP.
  • Here's a trick for searching the site: Instead of using the built-in search, use Google. You can search for results on The Beauty Brains by formatting your searches like this:

    "terms(s) you want to find" site:thebeautybrains.com

    So to find info on Nerium, your search would look like this:

    "Nerium" site:thebeautybrains.com

    It's not perfect, but this method does sometimes find more links than I get with the built-in search on the site.
  • @NoahJenda: Thanks for the tip. We suggested our IT guy look into replacing our search function with Google Search but it hasn't happened yet. Oh wait a minute, maybe that's because Rozy told us to fire him!  
  • :D Taking advice from the pros, and by pros I mean someone who had too much of a big mouth to pass grade 9 science.