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Research suggests that excess ceramides will activate senescence in cells and ultimately accelerating aging.
This thesis paper (http://gradworks.umi.com/35/55/3555520.html) states that increased ceramide levels in meth addicts are responsible for the accelerated aging in the users.
I am curious about your thoughts on this. Topically, they are great moisturizers but can they penetrate to the viable cells beneath and cause problems?
Interesting. I’m not a biochemist but I don’t really know what to do with this information. We know from years of studies that ceramides are an important part of the skin’s moisture barrier and that topical application of ceramides can benefit skin. Now here’s a study that says increased ceramics levels (from meth use) are associated with accelerated aging.
Assuming this study is valid, I wonder if it’s a question of degree. What I mean is, does topical application of steroids boost ceramides by a small amount which provides some benefit while meth addition stimulates a massive boost which has negative consequences?Or, could it be a question of biochemical pathways? Maybe topically applied ceramides don’t interact with cells the same way that ceramides do when their product is stimulated by meth use.I don’t know but for now the balance of research shows that ceramides can be good anti-aging ingredients.
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