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Top 10 female enhancement creams: do they work?

Diane dares to ask: I was wondering how effective these female enhancement creams really are. I looked at ingredients on 2 brands (Venus Touch and Orexia) and it looks like the only thing that might cause some sensations are the peppermint oil or menthol. What do you think?

Sarah Bellum says:

I’ve never had the need for these products so I’ve never paid much attention to them before. But, wow, once you starting looking, they’re everywhere! Some of them look like they use a simple “tingling” agent, like menthol, to get the job done. Others have different “active” ingredients that they claim will take you to “the promised land.” In either case, real test data for these products is tough to find. So after talking it over with the other lobes of the Beauty Brains, the Right Brain and I put together this list rating these products according to the following criteria:

Active ingredients: What’s in the product that gives it a sexual sizzle?

[Note: As you’ll see when you read this list, many of these products are based on L-Argenine, an amino acid that has been linked to the production of nitric oxide, a chemical that helps promote sensation down-you-know-where. However, these studies were done on L-Argenine in the blood, not from a topical application like these products provide. Therefore, we’re skeptical. Other ingredients like menthol and niacin cause a mild irritation that creates a tingling sensation.]

Proof: What kind of data does the company present to back up their claims?

Cost: Is the product a big rip off or little rip off?

Ok, having said all that, let’s take a look at the top 10 female enhancement creams:

1. Alura

Active Ingredients: L-arginine, Menthol

Cost: $15 for 10 applications ($1.50 per use)

Proof: None provided

Worth trying? Nope. This one’s almost double the price of some of the others and doesn’t seem to offer any added benefit.

2. Climatique

Active ingredients: L-Arginine, Niacin, and Menthol. We’ve talked about L-arg and Menthol above. Niacin can provide a topical sensation.

Cost: $24.95 for 20 to 30 uses. (About $1.00 per use)

Proof: According to the website: “Original Climatique was evaluated by the research department of world famous Institute for Advanced Study of Human Sexuality. Focus groups, clinicians and sexual scientists agreed with the women of all ages that Original Climatique deserved an unqualified recommendation for use as a sexual enhancer and a pleasure product.”

Worth trying? Hard to tell. I’m not sure what this endorsement means and the niacin scares me a bit – maybe too much sensation if you know what I mean

3. Orexia

Active ingredient: menthol

Proof: None.

Cost: $49 per jar of unknown size

Worth trying? No way am I paying 50 bucks for menthol!

4. Senstra

Active ingredient: L-Argenine

Proof: Same as #1 and 2 above.

Cost: $27.95 for 2 oz.

Worth trying? Nothing compelling here. Keep scrolling.

5. Vazoplex

Active ingredient: They won’t tell us! There’s nothing on the website that describes what’s actually in the product. A huge red flag!

Proof: You’re kidding, right? They won’t even say what’s in it!

Cost: $19.00 for a month supply. How many times would YOU use it in a month???

Worth trying? Forget it!

6. V Cream

Active ingredient: L-argenine, menthol, Damiana, Maca, Ginseng, Ginkgo Biloba.

Proof: None.

Cost: $44.00 per jar of unknown size.

Worth trying? More of the same.

7. Venus Touch

Active ingredient: Arginine and Ornithine, more nitric acid stimulation via amino acids.

Proof: Nothing substantial.

Cost: $19.95 for 20 to 30 uses (<$1.00 per use)

Worth trying? I’ll pass.

8. Vigel

Active ingredient: L-Arginine

Proof: There are references to clinical studies on L-Arginine but they don’t indicate how the L-Arginine was applied. Could have been ingested? Can’t tell for sure.

Cost: $24.95 per bottle (approx. 30 applications) (< $1.00 per use)

Worth trying? Well, at least it’s cheap!

9. Vigorelle

Active ingredients: Damiana Leaf, Suma Root, Motherwort, Wild Yam, Ginkgo Biloba, Peppermint Leaf. (Peppermint has an effect similar to menthol.)Cost: $59.95 for 30 applications ($2 per use)

Proof: None.

Cost: $59.95 for 2 ounces

Worth trying? No thanks, due to lack of proof and high price.

10. Zestra

Active Ingredients: Borage Seed Oil, Evening Primrose Oil, Coleus Extract, Vitamin C, Vitamin E, and natural fragrance.

Proof: Surprisingly, this is the only product that claims to NOT work through irritation. Unlike niacin and menthol, Zestra uses a different mechanism. Here’s what they say about their study results: “The Phase 3-type study evaluated the efficacy and safety of Zestra(R), compared to placebo oil in 256 women diagnosed with acquired mixed interest/desire/arousal/orgasm disorders in conditions of home use in conjunction with sexual activities. “Zestra was well-tolerated, and no serious adverse events (SAEs) were associated with study participants’ use of the product,” David M. Ferguson, PhD, MD, FACCP, the study’s clinical director, said.”

Cost: $17 for 9 uses ($1.80 per use)

Worth trying? Could be. Zestra is a bit more expensive per use, but it’s the only product that seems even remotely legitimate in my opinion. I’d bet my money on this one.

The Beauty Brains bottom line:

I’m not convinced there’s substantial research showing ANY of these really do anything beyond providing some surface tingling. But if you really want to try one, it looks like Zestra could be the best of the bunch.


What do YOU think? Have you tried any of these? Would you? If you would, would you tell anyone? Let’s find out! Leave a comment and share your salacious stories with the rest of the Beauty Brains community.

Comments on this entry are closed.

  • PA December 5, 2013, 7:36 pm

    For what it’s worth, Zestra is recomended by the Stanford Female Sexual Medicine Program. See this article:

    A woman with sexual arousal disorder should be evaluated by a clinician who is familiar with the field of female sexual medicine. A thorough psychosocial and medical evaluation should be carried out. Once the diagnosis is made, treatment options are reviewed. These include but are not limited to: sex therapy, relationship therapy, discontinuation of certain medications, off-label use of Viagra, Wellbutrin, and testosterone, Zestra lotion, EROS clitoral therapy device, herbal treatments such as ArginMax, vibrator therapy, lubricant use, and hormone therapy, such as topical estrogen.

    Also it has (or had a few years ago) over a hundred positive reviews on Drugstore.com.

  • Amber June 30, 2014, 1:37 am

    Have you actually tried any of these products?

    • admin June 30, 2014, 3:15 am


      • babzy February 23, 2017, 6:57 am

        Pretty much a pointless site then, other than to state your own opinion on price.

  • M. Carlson May 18, 2015, 3:58 pm


    Does age affect the use in any way?

    • Randy Schueller May 18, 2015, 4:12 pm

      M. Carlon: Sorry but that’s not really our area of expertise so I don’t know.

  • O. Olive September 30, 2015, 8:20 am

    Are you in any way, personal or business, related to any of the products included in your analysis?

  • a. Cornelius December 1, 2015, 11:45 am

    I personally use one called “O”. It’s amazing and totally worth it. You only need a pea size. The container lasts for a couple of months, depending on how often you use it. It runs $15-$20 depending on where you buy it.

    • Carol March 29, 2017, 5:04 pm

      what is “O” that Cornelius mentioned Dec 1, 2015

    • Lisa September 25, 2019, 8:13 am

      What is name of O and where do you get from

  • Nichelle December 30, 2015, 1:23 am

    Thank you for this! I was wondering what ingredient it was that hyped up the sensation and it looks like the common ingredient in all of these is menthol. I attended a Pure Romance party last weekend and thought I’d give one of their enhancement creams a try and bought the “O” one. AND OH MY GOD DOES IT EVER WORK! Like, instantly, and for a very long time. I’ve never tried any of the other ones in your article, but that one was definitely worth the money!

    • Eileen September 13, 2019, 10:51 am

      Could you please tell me where the “O” can be purchased? In my quest o find something this is the most positive one I’ve seen.
      Thank you.

  • Freeda January 30, 2016, 12:30 am

    Wait, so you haven’t actually tested the products? This is a pointless article based on speculation and guesswork. Lift your game folks.

    • Randy Schueller January 30, 2016, 8:13 am

      The purpose of this article was to review female enhancement creams based on active ingredient, evidence that they work, and price. We did not include personal testing. Sorry if that wasn’t enough for you.

    • Shaking my head May 7, 2016, 11:02 pm

      Yeah, I agree…the article isn’t helpful. At all. Obviously wasn’t meant to be.
      “Do they work?”…was never answered. The comments on “O” are at least by people who tried the product.

  • marsha March 19, 2016, 11:04 am

    please reply to my email address where do you buy zestra besides online? and where can you get this devise for ciltosis stimalation and how much ?EROS i belive its called

  • delores September 8, 2016, 4:02 pm

    i cant get an orgasm. please let me know of product which works, i tried zesta nothing happened. please reply, delores also does device called eros work,,,,,,,i need help bad thanks, dee

    • Amada Schick September 10, 2016, 7:08 am

      Hi Deloris
      I work with a dermatologist in willowbrook: Dr Cheung Dermatology and Laser Center. Dr Cheung specializes in hormone therapy. I’m 50 years old and had not had an orgasam in 20 years except in my sleep. She tested my hormones and found they were very low.

      Once my hormones were optimized, she did Diva vaginal resurfacing along with the PRP “O” shot injected in you clitoris and urethra. Two weeks later, I had my first vaginal orgasm. I might need another shot, but it’s certainly worth it. There are many Doctors who do this sort of work. Biote pellets for hormone they work and are safe along with the O shot. Read into it hopefully this helps. Have your hormones checked that’s the first step, you want to be on the high end of hormone range not within range, that’s what we call optimizing your hormones.

      • Carole May 5, 2019, 1:36 am

        I have had surgeries so I no longer have hormone issues however do you think the injections would still be beneficial? I have NEVER had a vaginal orgasm.

  • Marilyn September 28, 2016, 11:16 pm

    At 65 and after a lot of surgery in my female area, I’d been unable to have an orgasm on 20 years by any means. I bought a product in Wal-Mart for $24.95. I used 1 drop to massage on the clot and usually could achieve orgasm in 2 minutes. Sex became fun and fulfilling for my husband again. Try whatever they’re selling. It could change your life.

    • Jennifer December 20, 2016, 11:10 pm

      Please share the name of the product you bought at Wal-Mart. Thank you

    • Nancy November 24, 2019, 8:41 pm

      Name of product you purchased at Walmart for $25 please

  • Mother of 2 January 27, 2017, 7:47 pm

    I think this was very discouraging to women who truly have sexual problems. Perhaps it would have been more beneficial if you had actually tried the products or just not wrote it at all.

    • JustMe July 4, 2017, 10:55 am

      I wholeheartedly agree! I came here looking for answers not opinions. I feel mislead.

  • mary smith July 6, 2017, 8:43 pm

    vigorelle not bad…Orexia the best.

  • Erin January 2, 2018, 1:19 am

    Everyone responds different to stimulating creams/gels (I HATE cooling sensations so menthol is OUT), so I appreciate a list like this to help me quickly decide which ones (if any) are worth my time and money to try. I think some people aren’t realizing they can use this information that way; to narrow down what to even bother trying or doing more research on (such as reading reviews of personal experiences). If money is no object to you go ahead and try everything under the sun that someone claimed worked for them, but as a frugal person I appreciate this information.

  • Barbara January 25, 2018, 12:46 pm

    I have used the ‘O’ My gel for years and it is the best ! I’ve tried several different ones and this is by far the best! Not too expensive and last quite awhile. A small amount goes along way. I achieve orgasm in a matter of minutes. The more often you use the better it gets. Highly recommended. Sometimes hard to find in the US, not sure why.

  • fOru February 11, 2018, 9:22 pm

    G Stimulating Gel VS Hersolution Gel VS Vigorelle

    Which product is exciting and can you feel more orgasm? please recommend

  • AO February 18, 2018, 9:17 am

    I have used Zestra and it did help me to achieve orgasm

  • Ginny May 25, 2018, 6:26 am

    Try using Me4her. They offer free samples as well so you get to actually test the product without worrying about “money-wasted-on-a-wrong-product”.