≡ Menu

Top 10 female enhancement creams: do they work?

Diane dares to ask: I was wondering how effective these female enhancement creams really are. I looked at ingredients on 2 brands (Venus Touch and Orexia) and it looks like the only thing that might cause some sensations are the peppermint oil or menthol. What do you think?

Sarah Bellum says:

I’ve never had the need for these products so I’ve never paid much attention to them before. But, wow, once you starting looking, they’re everywhere! Some of them look like they use a simple “tingling” agent, like menthol, to get the job done. Others have different “active” ingredients that they claim will take you to “the promised land.” In either case, real test data for these products is tough to find. So after talking it over with the other lobes of the Beauty Brains, the Right Brain and I put together this list rating these products according to the following criteria:

Active ingredients: What’s in the product that gives it a sexual sizzle?

[Note: As you’ll see when you read this list, many of these products are based on L-Argenine, an amino acid that has been linked to the production of nitric oxide, a chemical that helps promote sensation down-you-know-where. However, these studies were done on L-Argenine in the blood, not from a topical application like these products provide. Therefore, we’re skeptical. Other ingredients like menthol and niacin cause a mild irritation that creates a tingling sensation.]

Proof: What kind of data does the company present to back up their claims?

Cost: Is the product a big rip off or little rip off?

Ok, having said all that, let’s take a look at the top 10 female enhancement creams:

1. Alura

Active Ingredients: L-arginine, Menthol

Cost: $15 for 10 applications ($1.50 per use)

Proof: None provided

Worth trying? Nope. This one’s almost double the price of some of the others and doesn’t seem to offer any added benefit.

2. Climatique

Active ingredients: L-Arginine, Niacin, and Menthol. We’ve talked about L-arg and Menthol above. Niacin can provide a topical sensation.

Cost: $24.95 for 20 to 30 uses. (About $1.00 per use)

Proof: According to the website: “Original Climatique was evaluated by the research department of world famous Institute for Advanced Study of Human Sexuality. Focus groups, clinicians and sexual scientists agreed with the women of all ages that Original Climatique deserved an unqualified recommendation for use as a sexual enhancer and a pleasure product.”

Worth trying? Hard to tell. I’m not sure what this endorsement means and the niacin scares me a bit – maybe too much sensation if you know what I mean

3. Orexia

Active ingredient: menthol

Proof: None.

Cost: $49 per jar of unknown size

Worth trying? No way am I paying 50 bucks for menthol!

4. Senstra

Active ingredient: L-Argenine

Proof: Same as #1 and 2 above.

Cost: $27.95 for 2 oz.

Worth trying? Nothing compelling here. Keep scrolling.

5. Vazoplex

Active ingredient: They won’t tell us! There’s nothing on the website that describes what’s actually in the product. A huge red flag!

Proof: You’re kidding, right? They won’t even say what’s in it!

Cost: $19.00 for a month supply. How many times would YOU use it in a month???

Worth trying? Forget it!

6. V Cream

Active ingredient: L-argenine, menthol, Damiana, Maca, Ginseng, Ginkgo Biloba.

Proof: None.

Cost: $44.00 per jar of unknown size.

Worth trying? More of the same.

7. Venus Touch

Active ingredient: Arginine and Ornithine, more nitric acid stimulation via amino acids.

Proof: Nothing substantial.

Cost: $19.95 for 20 to 30 uses (<$1.00 per use)

Worth trying? I’ll pass.

8. Vigel

Active ingredient: L-Arginine

Proof: There are references to clinical studies on L-Arginine but they don’t indicate how the L-Arginine was applied. Could have been ingested? Can’t tell for sure.

Cost: $24.95 per bottle (approx. 30 applications) (< $1.00 per use)

Worth trying? Well, at least it’s cheap!

9. Vigorelle

Active ingredients: Damiana Leaf, Suma Root, Motherwort, Wild Yam, Ginkgo Biloba, Peppermint Leaf. (Peppermint has an effect similar to menthol.)Cost: $59.95 for 30 applications ($2 per use)

Proof: None.

Cost: $59.95 for 2 ounces

Worth trying? No thanks, due to lack of proof and high price.

10. Zestra

Active Ingredients: Borage Seed Oil, Evening Primrose Oil, Coleus Extract, Vitamin C, Vitamin E, and natural fragrance.

Proof: Surprisingly, this is the only product that claims to NOT work through irritation. Unlike niacin and menthol, Zestra uses a different mechanism. Here’s what they say about their study results: “The Phase 3-type study evaluated the efficacy and safety of Zestra(R), compared to placebo oil in 256 women diagnosed with acquired mixed interest/desire/arousal/orgasm disorders in conditions of home use in conjunction with sexual activities. “Zestra was well-tolerated, and no serious adverse events (SAEs) were associated with study participants’ use of the product,” David M. Ferguson, PhD, MD, FACCP, the study’s clinical director, said.”

Cost: $17 for 9 uses ($1.80 per use)

Worth trying? Could be. Zestra is a bit more expensive per use, but it’s the only product that seems even remotely legitimate in my opinion. I’d bet my money on this one.

The Beauty Brains bottom line:

I’m not convinced there’s substantial research showing ANY of these really do anything beyond providing some surface tingling. But if you really want to try one, it looks like Zestra could be the best of the bunch.


What do YOU think? Have you tried any of these? Would you? If you would, would you tell anyone? Let’s find out! Leave a comment and share your salacious stories with the rest of the Beauty Brains community.

{ 13 comments… add one }

  • PA December 5, 2013, 7:36 pm

    For what it’s worth, Zestra is recomended by the Stanford Female Sexual Medicine Program. See this article:

    A woman with sexual arousal disorder should be evaluated by a clinician who is familiar with the field of female sexual medicine. A thorough psychosocial and medical evaluation should be carried out. Once the diagnosis is made, treatment options are reviewed. These include but are not limited to: sex therapy, relationship therapy, discontinuation of certain medications, off-label use of Viagra, Wellbutrin, and testosterone, Zestra lotion, EROS clitoral therapy device, herbal treatments such as ArginMax, vibrator therapy, lubricant use, and hormone therapy, such as topical estrogen.

    Also it has (or had a few years ago) over a hundred positive reviews on Drugstore.com.

  • Amber June 30, 2014, 1:37 am

    Have you actually tried any of these products?

    • admin June 30, 2014, 3:15 am


  • M. Carlson May 18, 2015, 3:58 pm


    Does age affect the use in any way?

    • Randy Schueller May 18, 2015, 4:12 pm

      M. Carlon: Sorry but that’s not really our area of expertise so I don’t know.

  • O. Olive September 30, 2015, 8:20 am

    Are you in any way, personal or business, related to any of the products included in your analysis?

  • a. Cornelius December 1, 2015, 11:45 am

    I personally use one called “O”. It’s amazing and totally worth it. You only need a pea size. The container lasts for a couple of months, depending on how often you use it. It runs $15-$20 depending on where you buy it.

  • Nichelle December 30, 2015, 1:23 am

    Thank you for this! I was wondering what ingredient it was that hyped up the sensation and it looks like the common ingredient in all of these is menthol. I attended a Pure Romance party last weekend and thought I’d give one of their enhancement creams a try and bought the “O” one. AND OH MY GOD DOES IT EVER WORK! Like, instantly, and for a very long time. I’ve never tried any of the other ones in your article, but that one was definitely worth the money!

  • Freeda January 30, 2016, 12:30 am

    Wait, so you haven’t actually tested the products? This is a pointless article based on speculation and guesswork. Lift your game folks.

    • Randy Schueller January 30, 2016, 8:13 am

      The purpose of this article was to review female enhancement creams based on active ingredient, evidence that they work, and price. We did not include personal testing. Sorry if that wasn’t enough for you.

    • Shaking my head May 7, 2016, 11:02 pm

      Yeah, I agree…the article isn’t helpful. At all. Obviously wasn’t meant to be.
      “Do they work?”…was never answered. The comments on “O” are at least by people who tried the product.

  • marsha March 19, 2016, 11:04 am

    please reply to my email address where do you buy zestra besides online? and where can you get this devise for ciltosis stimalation and how much ?EROS i belive its called

Leave a Comment