Cocktail effect

Dear Brains.

I just read your post about the Think Dirty-app, and it reminded me of something I've been wondering about from time to time:

What is the deal with the cocktail effect when it comes to cosmetic ingredients? I've heard a lot of "experts" say that we don't know what happens when we are exposed to so many chemicals, and how they work together. I would love to hear what you think, because I don't know what to think about it. 

By the way, I love what you're saying about people being way more likely to develop cancer from cigarettes, alcohol and sun. I really have a hard time taking anyone that drinks alcohol regularly and/or smokes seriously when they talk about how we should worry about what we put on our skin.

I hope you can answer my question! :) 
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